Recovery after spinal cord injury

Spinal cord injury (SCI) often causes severe and permanent disabilities due to the regenerative failure of severed axons. Here we report significant locomotor recovery of both hindlimbs after a complete spinal cord crush. This is achieved by the unilateral transduction of cortical motoneurons with an AAV expressing hyper-IL-6 (hIL-6), a potent designer cytokine stimulating JAK/STAT3 signaling… Continue reading Recovery after spinal cord injury

Reversing aging in the eye

Scientists develop a gene therapy to reverse age-related vision loss andglaucoma damage in mice Harvard Stem Cell Institute (HSCI) scientists are part of a team that has successfully restored vision in mice by turning back the clock in aged eye cells in the retina to recapture youthful gene function. The team’s work, published in the journal Nature, is the… Continue reading Reversing aging in the eye